Note: This is the 2024鈥�2025 eCalendar. Current program and course information is now found in the 91导航视频 Course Catalogue at .
Overview
BIEN : Forward and reverse engineering of biomolecular systems. Principles of biomolecular thermodynamics and kinetics. Structure and function of the main classes of biomolecules including proteins, nucleic acids, and lipids. Biomolecular systems as mechanical, chemical, and electrical systems. Rational design and evolutionary methods for engineering functional proteins, nucleic acids, and gene circuits. Rational design topics include molecular modeling, positive and negative design paradigms, simulation and optimization of equilibrium and kinetic properties, design of catalysts, sensors, motors, and circuits. Evolutionary design topics include evolutionary mechanisms, fitness landscapes, directed evolution of proteins, metabolic pathways, and gene circuits. Systems biology and synthetic biology.
Terms: Fall 2024
Instructors: Xia, Yu; Coulombe-Huntington, Jasmin (Fall)
Prerequisite(s): BIEN 200 or permission of instructor.
(3-0-6)
