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DESCRIPTION:Mechanistic modeling of immune cell activation in cancer \n\nSt
 acey Finley\, University of Southern California\n	Tuesday November 2\, 12-1
 pm\n	Zoom Link: https://mcgill.zoom.us/j/85428056343\n\nAbstract: My resear
 ch group works in the area of mathematical oncology\, where we use mathema
 tical models to decipher the complex networks of reactions inside of cance
 r cells and interactions between cells. Immune cells use hundreds of bioch
 emical reactions to respond to their environment\, become activated\, and 
 kill cancer cells. Understanding the complexity of these reaction networks
  requires computational tools and mathematical models. We combine detailed
 \, mechanistic modeling with machine learning to study these networks\, be
 tter understand cancer and immune cells\, and predict ways to control tumo
 r growth. In this talk\, I will present our recent work aimed at predictin
 g the dynamics of immune cell behaviors across multiple scales: intracellu
 lar signaling pathways in CAR T cells\, the collective behavior of a heter
 ogeneous population of immune cells\, and tumor-immune interactions at the
  tissue scale. Our models generate novel mechanistic insight into immune c
 ell activation and predict the effects of immunotherapeutic strategies.\n
 \nBio: Stacey D. Finley is the Gordon S. Marshall Early Career Chair and A
 ssociate Professor of Biomedical Engineering at the University of Southern
  California. Dr. Finley received her B.S. in Chemical Engineering from Flo
 rida A & M University and obtained her Ph.D. in Chemical Engineering from 
 Northwestern University. She completed postdoctoral training at Johns Hopk
 ins University in the Department of Biomedical Engineering. Dr. Finley joi
 ned the faculty at USC in 2013\, and she leads the Computational Systems B
 iology Laboratory. Dr. Finley has joint appointments in the Departments of
  Chemical Engineering and Materials Science and Biological Science\, and s
 he is a member of the USC Norris Comprehensive Cancer Center. Dr. Finley i
 s also the Founding Director of the Center for Computational Modeling of C
 ancer at USC. Her research is supported by grants from NSF\, NIH\, and the
  American Cancer Society.\n
DTSTART:20211102T160000Z
DTEND:20211102T170000Z
LOCATION:CA\, QC
SUMMARY:QLS Seminar Series - Stacey Finley
URL:/qls/channels/event/qls-seminar-series-stacey-finl
 ey-333881
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